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High Prevalence of Central Adrenal Insufficiency in Patients with Prader-Willi Syndrome
Author(s) -
Roderick F. A. de Lind van Wijngaarden,
Barto J. Otten,
Dederieke A. M. Festen,
Koen F. M. Joosten,
Frank H. de Jong,
Fred C.G.J. Sweep,
Anita Hokken-Koelega
Publication year - 2008
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2007-2294
Subject(s) - medicine , metyrapone , interquartile range , morning , cortisol awakening response , hydrocortisone , adrenal insufficiency , endocrinology , body mass index , pediatrics
The annual death rate of Prader-Willi syndrome (PWS) patients is very high (3%). Many of these deaths are sudden and unexplained.

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