Open AccessAcyl and Total Ghrelin Are Suppressed Strongly by Ingested Proteins, Weakly by Lipids, and Biphasically by Carbohydrates
Author(s) -
Karen E. Foster-Schubert,
Joost Overduin,
Catherine E. Prudom,
Jianhua Liu,
Holly S. Callahan,
Bruce D. Gaylinn,
Michael O. Thorner,
David Cummings
Publication year - 2008
Publication title -
the journal of clinical endocrinology and metabolism/journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2007-2289
Subject(s) - ghrelin , postprandial , orexigenic , medicine , endocrinology , ingestion , carbohydrate , chemistry , hormone , biology , neuropeptide , insulin , receptor , neuropeptide y receptor
Ghrelin is an orexigenic hormone that can increase body weight. Its circulating levels increase before meals and are suppressed after food ingestion. Understanding the effects of specific types of ingested macronutrients on ghrelin regulation could facilitate the design of weight-reducing diets.