Growth Hormone Response during Oral Glucose Tolerance Test: The Impact of Assay Method on the Estimation of Reference Values in Patients with Acromegaly and in Healthy Controls, and the Role of Gender, Age, and Body Mass Index | Zendy

Ayman M. Arafat | Zendy; Matthias Möhlig | Zendy; Martin O. Weickert | Zendy; F. H. Perschel | Zendy; J Purschwitz | Zendy; Joachim Spranger | Zendy; Christian J. Strasburger | Zendy; Christof Schöfl | Zendy; A. Pfeiffer | Zendy

Open Access

Growth Hormone Response during Oral Glucose Tolerance Test: The Impact of Assay Method on the Estimation of Reference Values in Patients with Acromegaly and in Healthy Controls, and the Role of Gender, Age, and Body Mass Index

Author(s) -

Ayman M. Arafat,

Matthias Möhlig,

Martin O. Weickert,

F. H. Perschel,

J Purschwitz,

Joachim Spranger,

Christian J. Strasburger,

Christof Schöfl,

A. Pfeiffer

Publication year - 2008

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2007-2084

Subject(s) - acromegaly , medicine , liter , body mass index , endocrinology , growth hormone , basal (medicine) , confounding , confidence interval , pituitary disease , gastroenterology , hormone , insulin

Besides the measurement of IGF-I, GH suppression during an oral glucose tolerance test is recommended to assess the biochemical status in acromegaly. However, the development of highly sensitive and specific GH assays necessitates a critical reevaluation of criteria for diagnosis and follow-up of disease activity.

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