Adipose Tissue Lipin-1 Expression Is Correlated with Peroxisome Proliferator-Activated Receptor α Gene Expression and Insulin Sensitivity in Healthy Young Men
Author(s) -
Jimmy Donkor,
Lauren M. Sparks,
Hui Xie,
Steven R. Smith,
Karen Reue
Publication year - 2007
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2007-1535
Subject(s) - medicine , endocrinology , adipose tissue , respiratory quotient , insulin resistance , biology , peroxisome , triglyceride , gene expression , peroxisome proliferator activated receptor , lipolysis , insulin , adipocyte , receptor , beta oxidation , metabolism , gene , biochemistry , cholesterol
Lipin-1 functions in adipocyte triglyceride biosynthesis and in the regulation of gene expression, both of which may influence metabolic homeostasis.
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