Open AccessDose-Dependent Regulation of High-Density Lipoprotein Metabolism with Rosuvastatin in the Metabolic Syndrome
Author(s) -
Esther M.M. Ooi,
Gerald F. Watts,
Paul J. Nestel,
Dmitri Sviridov,
Anh Hoang,
P. Hugh R. Barrett
Publication year - 2008
Publication title -
the journal of clinical endocrinology and metabolism/journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2007-0854
Subject(s) - medicine , endocrinology , rosuvastatin , apolipoprotein b , metabolic syndrome , cholesterol , catabolism , high density lipoprotein , lipoprotein , triglyceride , chemistry , metabolism , diabetes mellitus
Low plasma concentration of high-density lipoprotein (HDL) cholesterol is a risk factor for cardiovascular disease and a feature of the metabolic syndrome. Rosuvastatin has been shown to increase HDL cholesterol concentration, but the mechanisms remain unclear.