Dietary Macronutrient Content Alters Cortisol Metabolism Independently of Body Weight Changes in Obese Men
Author(s) -
Roland H. Stimson,
Alexandra M. Johnstone,
Natalie Homer,
Deborah J. Wake,
Nicholas Morton,
Ruth Andrew,
G. E. Lobley,
Brian R. Walker
Publication year - 2007
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2007-0692
Subject(s) - endocrinology , obesity , medicine , metabolism , context (archaeology) , glucocorticoid , carbohydrate metabolism , biology , insulin , paleontology
Dietary macronutrient composition influences cardiometabolic health independently of obesity. Both dietary fat and insulin alter glucocorticoid metabolism in rodents and, acutely, in humans. However, whether longer-term differences in dietary macronutrients affect cortisol metabolism in humans and contribute to the tissue-specific dysregulation of cortisol metabolism in obesity is unknown.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom