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Dietary Macronutrient Content Alters Cortisol Metabolism Independently of Body Weight Changes in Obese Men
Author(s) -
Roland H. Stimson,
Alexandra M. Johnstone,
Natalie Homer,
Deborah J. Wake,
Nicholas Morton,
Ruth Andrew,
G. E. Lobley,
Brian R. Walker
Publication year - 2007
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2007-0692
Subject(s) - endocrinology , obesity , medicine , metabolism , context (archaeology) , glucocorticoid , carbohydrate metabolism , biology , insulin , paleontology
Dietary macronutrient composition influences cardiometabolic health independently of obesity. Both dietary fat and insulin alter glucocorticoid metabolism in rodents and, acutely, in humans. However, whether longer-term differences in dietary macronutrients affect cortisol metabolism in humans and contribute to the tissue-specific dysregulation of cortisol metabolism in obesity is unknown.

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