Concomitant Reduction of Low-Density Lipoprotein-Cholesterol and Biomarkers of Inflammation with Low-Dose Simvastatin Therapy in Patients with Type 1 Diabetes | Zendy

Ishwarlal Jialal | Zendy; Eric Miguelino | Zendy; Steven C. Griffen | Zendy; Sridevi Devaraj | Zendy

Open Access

Concomitant Reduction of Low-Density Lipoprotein-Cholesterol and Biomarkers of Inflammation with Low-Dose Simvastatin Therapy in Patients with Type 1 Diabetes

Author(s) -

Ishwarlal Jialal,

Eric Miguelino,

Steven C. Griffen,

Sridevi Devaraj

Publication year - 2007

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2007-0453

Subject(s) - simvastatin , concomitant , type 2 diabetes , medicine , inflammation , low density lipoprotein , reduction (mathematics) , diabetes mellitus , cholesterol , endocrinology , cardiology , mathematics , geometry

Cardiovascular disease is a major cause of mortality in type 1 diabetes (TIDM). TIDM is a proinflammatory state. Whereas there is consensus on lipid management in type 2 diabetes, there is a lack of data in type 1 diabetes. In addition to benefits on the lipid profile, statin therapy is antiinflammatory.

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