Nephroblastoma Overexpressed/Cysteine-Rich Protein 61/Connective Tissue Growth Factor/Nephroblastoma Overexpressed Gene-3 (NOV/CCN3), a Selective Adrenocortical Cell Proapoptotic Factor, Is Down-Regulated in Childhood Adrenocortical Tumors | Zendy

Mabrouka Doghman | Zendy; Malika Arhatte | Zendy; Hélène Thibout | Zendy; Giovanna Assis Rodrigues | Zendy; Juliana de Moura | Zendy; Sébastien Grosso | Zendy; Aliico West | Zendy; M. Laurent | Zendy; Jean-Christophe Mas | Zendy; A. Bongain | Zendy; Gerard P. Zambetti | Zendy; Bonald C. Figueiredo | Zendy; Patrick Auberger | Zendy; Cécile Martinerie | Zendy; Enzo Lalli | Zendy

Open Access

Nephroblastoma Overexpressed/Cysteine-Rich Protein 61/Connective Tissue Growth Factor/Nephroblastoma Overexpressed Gene-3 (NOV/CCN3), a Selective Adrenocortical Cell Proapoptotic Factor, Is Down-Regulated in Childhood Adrenocortical Tumors

Author(s) -

Mabrouka Doghman,

Malika Arhatte,

Hélène Thibout,

Giovanna Assis Rodrigues,

Juliana de Moura,

Sébastien Grosso,

Aliico West,

M. Laurent,

Jean-Christophe Mas,

A. Bongain,

Gerard P. Zambetti,

Bonald C. Figueiredo,

Patrick Auberger,

Cécile Martinerie,

Enzo Lalli

Publication year - 2007

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2007-0342

Subject(s) - steroidogenic factor 1 , connective tissue , biology , growth factor , context (archaeology) , cancer research , endocrinology , gene , medicine , pathology , transcription factor , genetics , receptor , paleontology , nuclear receptor

Childhood adrenocortical tumors (ACTs) have a fetal adrenal phenotype and overexpress steroidogenic factor-1 (SF-1). Nephroblastoma overexpressed (NOV)/cysteine-rich protein 61/connective tissue growth factor/nephroblastoma overexpressed gene-3 mRNA is significantly down-regulated in childhood ACTs.

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