Measurement of Salivary Cortisol Concentration in the Assessment of Adrenal Function in Critically Ill Subjects: A Surrogate Marker of the Circulating Free Cortisol | Zendy

Baha M. Arafah | Zendy; Fumie J. Nishiyama | Zendy; H. Tlaygeh | Zendy; Rana Hejal | Zendy

Open Access

Measurement of Salivary Cortisol Concentration in the Assessment of Adrenal Function in Critically Ill Subjects: A Surrogate Marker of the Circulating Free Cortisol

Author(s) -

Baha M. Arafah,

Fumie J. Nishiyama,

H. Tlaygeh,

Rana Hejal

Publication year - 2007

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2007-0181

Subject(s) - cosyntropin , adrenal function , medicine , endocrinology , critically ill , adrenal insufficiency , albumin , hydrocortisone , saliva , surrogate endpoint , adrenocorticotropic hormone , hormone

Baseline and cosyntropin-stimulated serum (total and free) and salivary cortisol concentrations were measured, in the early afternoon, in 51 critically ill patients and healthy subjects. Patients were stratified according to their serum albumin at the time of testing: those whose serum albumin levels were 2.5 gm/dl or less vs. others whose levels were greater than 2.5 gm/dl.

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