Open AccessEarly Recombinant Human Growth Hormone Treatment in Glucocorticoid-Treated Children with Juvenile Idiopathic Arthritis: A 3-Year Randomized Study
Author(s) -
Dominique Simon,
AnneMarie Prieur,
Pierre Quartier,
Jean Charles Ruiz,
Paul Czernichow
Publication year - 2007
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2006-2877
Subject(s) - medicine , endocrinology , glucocorticoid , adverse effect , bone age , insulin , lean body mass , body weight
Long-term glucocorticoid therapy adversely affects growth and body composition in children with juvenile idiopathic arthritis (JIA). In previous studies, recombinant human GH (rhGH) halted the progression of these complications without inducing catch-up growth.
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