Bexarotene-Induced Hypothyroidism: Bexarotene Stimulates the Peripheral Metabolism of Thyroid Hormones | Zendy

Johannes W. A. Smit | Zendy; Marcel P. M. Stokkel | Zendy; Alberto M. Pereira | Zendy; Johannes A. Romijn | Zendy; Theo J. Visser | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Bexarotene-Induced Hypothyroidism: Bexarotene Stimulates the Peripheral Metabolism of Thyroid Hormones

Author(s) -

Johannes W. A. Smit,

Marcel P. M. Stokkel,

Alberto M. Pereira,

Johannes A. Romijn,

Theo J. Visser

Publication year - 2007

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2006-2822

Subject(s) - bexarotene , medicine , endocrinology , thyroid , hormone , retinoid , retinoid x receptor , chemistry , nuclear receptor , retinoic acid , biochemistry , transcription factor , gene

Therapy with the retinoid X receptor agonist bexarotene is associated with hypothyroidism caused by decreased pituitary TSH secretion. To evaluate the effects of bexarotene on peripheral thyroid hormone metabolism, we performed a study in athyreotic subjects on a fixed substitution dose with L-T4.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research