Altered Platelet Plug Formation in Hyperthyroidism and Hypothyroidism | Zendy

Monika Homoncik | Zendy; Alois Gessl | Zendy; Arnulf Ferlitsch | Zendy; Bernd Jilma | Zendy; H. Vierhapper | Zendy

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Altered Platelet Plug Formation in Hyperthyroidism and Hypothyroidism

Author(s) -

Monika Homoncik,

Alois Gessl,

Arnulf Ferlitsch,

Bernd Jilma,

H. Vierhapper

Publication year - 2007

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2006-2644

Subject(s) - medicine , platelet , euthyroid , von willebrand factor , endocrinology , hemostasis , subclinical infection , platelet activation , thyroid function tests , epinephrine , thyroid

Patients with thyroid diseases have abnormalities of blood coagulation including an alteration of von Willebrand factor (vWF) levels. Because vWF plays an important role in primary hemostasis, we hypothesized that heightened and decreased vWF levels in hyper- and hypothyroidism enhance and decrease platelet plug formation, respectively.

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