Relationships between Desacylated and Acylated Ghrelin and Insulin Sensitivity in the Metabolic Syndrome | Zendy

Rocco Barazzoni | Zendy; Michela Zanetti | Zendy; Clara Ferreira | Zendy; Pierandrea Vinci | Zendy; Alessia Pirulli | Zendy; M. Mucci | Zendy; Franca Dore | Zendy; Maurizio Fonda | Zendy; B. Ciocchi | Zendy; Luigi Cattin | Zendy; Gianfranco Guarnieri | Zendy

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Relationships between Desacylated and Acylated Ghrelin and Insulin Sensitivity in the Metabolic Syndrome

Author(s) -

Rocco Barazzoni,

Michela Zanetti,

Clara Ferreira,

Pierandrea Vinci,

Alessia Pirulli,

M. Mucci,

Franca Dore,

Maurizio Fonda,

B. Ciocchi,

Luigi Cattin,

Gianfranco Guarnieri

Publication year - 2007

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2006-2527

Subject(s) - ghrelin , endocrinology , insulin resistance , medicine , context (archaeology) , metabolic syndrome , insulin , growth hormone receptor , obesity , insulin sensitivity , growth hormone , hormone , biology , paleontology

Metabolic syndrome shows clustered metabolic abnormalities with major roles for insulin resistance and obesity. Ghrelin is a gastric hormone whose total plasma concentration (T-Ghr) is associated positively with insulin sensitivity and is reduced in obesity. Ghrelin circulates in acylated (A-Ghr) and desacylated (D-Ghr) forms, but their potential differential associations with insulin resistance and whether they are differentially altered in obesity remain undefined.

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