The Expression of NAD(P)H:Quinone Oxidoreductase 1 Is High in Human Adipose Tissue, Reduced by Weight Loss, and Correlates with Adiposity, Insulin Sensitivity, and Markers of Liver Dysfunction | Zendy

Jenny Palming | Zendy; Kajsa Sjöholm | Zendy; Margareta Jernås | Zendy; Theodore C. Lystig | Zendy; Anders Gummesson | Zendy; Stefano Romeo | Zendy; Lars Lönn | Zendy; Malin Lönn | Zendy; Björn Carlsson | Zendy; Lena Carlsson | Zendy

Open Access

The Expression of NAD(P)H:Quinone Oxidoreductase 1 Is High in Human Adipose Tissue, Reduced by Weight Loss, and Correlates with Adiposity, Insulin Sensitivity, and Markers of Liver Dysfunction

Author(s) -

Jenny Palming,

Kajsa Sjöholm,

Margareta Jernås,

Theodore C. Lystig,

Anders Gummesson,

Stefano Romeo,

Lars Lönn,

Malin Lönn,

Björn Carlsson,

Lena Carlsson

Publication year - 2007

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2006-2476

Subject(s) - endocrinology , medicine , adipose tissue , adipocyte , biology , steatosis , insulin resistance , insulin

We have previously identified nicotinamide adenine dinucleotide phosphate:quinone oxidoreductase 1 (NQO1), an enzyme involved in the protection against oxidative stress, as a gene predominantly expressed in human adipocytes. Studies in mice deficient in NQO1 activity suggest that NQO1 may also play an important role in metabolism.

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