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Increased Osteoprotegerin Levels in Cushing’s Syndrome Are Associated with an Adverse Cardiovascular Risk Profile
Author(s) -
Andrea Dovio,
Barbara Allasino,
Enrico Palmas,
M. Ventura,
Anna Pia,
L. Saba,
Emiliano Aroasio,
Massimo Terzolo,
Alberto Angeli
Publication year - 2007
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2006-2283
Subject(s) - osteoprotegerin , medicine , context (archaeology) , endocrinology , adverse effect , disease , cardiology , receptor , biology , paleontology , activator (genetics)
Patients with Cushing's syndrome (CS) have a mortality rate four times higher than age- and sex-matched subjects, mainly due to cardiovascular events. Serum osteoprotegerin (OPG) levels are increased in patients with cardiovascular disease and/or excess bone resorption.

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