Endometrial Effects of Tibolone
Author(s) -
David F. Archer,
Susan L. Hendrix,
John C. Gallagher,
Janice Rymer,
Sven O. Skouby,
Alex Ferenczy,
Wil den Hollander,
V. M. Stathopoulos,
F.A. Helmond
Publication year - 2006
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2006-2207
Subject(s) - tibolone , medroxyprogesterone acetate , endometrium , medicine , endocrinology , estrogen , medroxyprogesterone
The Tibolone Histology of the Endometrium and Breast Endpoints Study is a multicenter, randomized, double-blind study designed to address the conflicting reports in the literature about the endometrial safety of tibolone (1.25 or 2.5 mg/d). Tibolone was compared with continuous combined conjugated equine estrogen (CEE) plus medroxyprogesterone acetate (MPA) (0.625 + 2.5 mg/d).
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