Combining Growth Hormone Releasing Hormone-Arginine and Synacthen Testing Diminishes the Cortisol Response | Zendy

S. Siyambalapitiya | Zendy; V. Ibbotson | Zendy; A. Doane | Zendy; Ezio Ghigo | Zendy; Michael J. Campbell | Zendy; Richard Ross | Zendy

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Combining Growth Hormone Releasing Hormone-Arginine and Synacthen Testing Diminishes the Cortisol Response

Author(s) -

S. Siyambalapitiya,

V. Ibbotson,

A. Doane,

Ezio Ghigo,

Michael J. Campbell,

Richard Ross

Publication year - 2006

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2006-2140

Subject(s) - medicine , endocrinology , arginine , insulin tolerance test , confidence interval , basal (medicine) , hormone , hydrocortisone , adrenocorticotropic hormone , insulin , biology , insulin resistance , insulin sensitivity , biochemistry , amino acid

The GHRH/arginine test and short synacthen test (SST) have been validated as safe alternatives to the insulin tolerance test for the assessment of the GH reserve and hypothalamic-pituitary-adrenal axis integrity, respectively. However, these two tests are usually performed separately. The objective was to see whether the synacthen and GHRH/arginine tests could be combined to save time and blood samples and minimize inconvenience to patients.

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