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Mortality in Patients Treated for Cushing’s Disease Is Increased, Compared with Patients Treated for Nonfunctioning Pituitary Macroadenoma
Author(s) -
Olaf M. Dekkers,
Nienke R. Biermasz,
Alberto M. Pereira,
Ferdinand Roelfsema,
Maarten O. van Aken,
J. H. C. Voormolen,
Johannes A. Romijn
Publication year - 2007
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2006-2112
Subject(s) - medicine , cushing's disease , hazard ratio , cohort , context (archaeology) , pituitary adenoma , standardized mortality ratio , transsphenoidal surgery , confidence interval , cohort study , pituitary tumors , proportional hazards model , cushing syndrome , adenoma , mortality rate , disease , paleontology , biology
Increased mortality in patients with pituitary tumors after surgical treatment has been reported. However, it is unknown to what extent excess mortality is caused by pituitary tumors and their treatment in general and to what extent by previous exposure to hormonal overproduction.

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