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Although the production and metabolic clearance rate of cortisol is increased during thyrotoxic state, the net effect on adrenocortical reserves is not clear.

the journal of clinical endocrinology and metabolism/journal of clinical endocrinology and metabolism

Plasma Adrenocorticotropin (ACTH) Values and Cortisol Response to 250 and 1 μg ACTH Stimulation in Patients with Hyperthyroidism before and after Carbimazole Therapy: Case-Control Comparative Study