Identifying Children at Risk for Polycystic Ovary Syndrome
Author(s) -
Robert L. Rosenfield
Publication year - 2006
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2006-2012
Subject(s) - polycystic ovary , trait , context (archaeology) , ovary , pathogenesis , medicine , biology , developmental psychology , psychology , endocrinology , insulin resistance , obesity , paleontology , computer science , programming language
Polycystic ovary syndrome (PCOS) appears to arise as a complex trait with contributions from both heritable and nonheritable factors. Polygenic influences appear to account for about 70% of the variance in pathogenesis. In view of this evidence for congenital contributions to the syndrome, childhood manifestations may be expected.
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