Effects of Simvastatin and Oral Contraceptive Agent on Polycystic Ovary Syndrome: Prospective, Randomized, Crossover Trial | Zendy

Beata Banaszewska | Zendy; Leszek Pawełczyk | Zendy; Robert Spaczyński | Zendy; James Dziura | Zendy; Antoni J. Dulęba | Zendy

Open Access

Effects of Simvastatin and Oral Contraceptive Agent on Polycystic Ovary Syndrome: Prospective, Randomized, Crossover Trial

Author(s) -

Beata Banaszewska,

Leszek Pawełczyk,

Robert Spaczyński,

James Dziura,

Antoni J. Dulęba

Publication year - 2006

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2006-1988

Subject(s) - polycystic ovary , hyperandrogenism , medicine , dyslipidemia , context (archaeology) , ovary , endocrinology , randomized controlled trial , simvastatin , biology , obesity , insulin resistance , paleontology

Polycystic ovary syndrome (PCOS) is associated with hyperandrogenism and cardiovascular risks including dyslipidemia and systemic inflammation. In vitro, statins decrease proliferation and steroidogenesis of ovarian theca-interstitial cells.

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