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Plasma Adiponectin Concentrations and Risk of Incident Breast Cancer
Author(s) -
Shelley S. Tworoger,
A. Heather Eliassen,
Theodoros Kelesidis,
Graham A. Colditz,
Walter C. Willett,
Christos S. Mantzoros,
Susan E. Hankinson
Publication year - 2007
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2006-1975
Subject(s) - medicine , breast cancer , adiponectin , body mass index , prospective cohort study , nurses' health study , menarche , confidence interval , obstetrics , endocrinology , cancer , gynecology , obesity , insulin resistance
Previous retrospective case-control studies suggest that adiponectin, an obesity-related hormone, is inversely associated with breast cancer risk, particularly in postmenopausal women; however, no prospective studies exist. Therefore, we conducted a prospective case-control study nested within the Nurses' Health Study (NHS) and NHSII cohorts examining the association between plasma adiponectin concentrations and breast cancer risk.

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