Aryl Hydrocarbon Receptor Interacting Protein Variants in Sporadic Pituitary Adenomas | Zendy

Run Yu | Zendy; Vivien Bonert | Zendy; Inbar Saporta | Zendy; Leslie J. Raffel | Zendy; Шломо Мелмед | Zendy

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Aryl Hydrocarbon Receptor Interacting Protein Variants in Sporadic Pituitary Adenomas

Author(s) -

Run Yu,

Vivien Bonert,

Inbar Saporta,

Leslie J. Raffel,

Шломо Мелмед

Publication year - 2006

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - Uncategorized

Resource type - Journals

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2006-1731

Subject(s) - pituitary tumors , acromegaly , germline mutation , germline , context (archaeology) , cancer research , pituitary neoplasm , pituitary adenoma , mutation , pathogenesis , medicine , endocrinology , biology , genetics , pituitary gland , gene , adenoma , hormone , growth hormone , paleontology

Proximal pathogenesis of pituitary tumors remains largely unclear. Recently, three heterozygous germline mutations were reported in the aryl hydrocarbon receptor interacting protein (AIP) gene in Finnish and Italian families with pituitary tumor predisposition and in Finnish patients harboring sporadic pituitary tumors.

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