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Cardiovascular Risk Factors and Ultrasound Evaluation of Intima-Media Thickness at Common Carotids, Carotid Bulbs, and Femoral and Abdominal Aorta Arteries in Patients with Classic Congenital Adrenal Hyperplasia due to 21-Hydroxylase Deficiency
Author(s) -
Paola Sartorato,
E. Zulian,
Stefano Benedini,
Barbara Mariniello,
Francesca Schiavi,
Franca Bilora,
Giovanni Battista Pozzan,
Nella Augusta Greggio,
Antonio Pagnan,
Franco Mantero,
Carla Scaroni
Publication year - 2007
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2006-1711
Subject(s) - medicine , endocrinology , insulin resistance , hyperandrogenism , blood pressure , insulin , intima media thickness , congenital adrenal hyperplasia , context (archaeology) , polycystic ovary , carotid arteries , paleontology , biology
In congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency, a tendency for obesity, high insulin, and high 24-h blood pressure levels has been reported in children and adolescents. Increased intima-media thickness (IMT) is considered a measure of subclinical atherosclerosis and a predictor of myocardial infarction and stroke.

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