Open AccessIdentification of an Aromatase Haplotype That Is Associated with Gene Expression and Postmenopausal Osteoporosis
Author(s) -
José A. Riancho,
Carmen Valero,
Angel Naranjo,
Dieter Morales-García,
Carolina Sañudo,
Marı́a T. Zarrabeitia
Publication year - 2006
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2006-1616
Subject(s) - single nucleotide polymorphism , haplotype , aromatase , medicine , allele , osteoporosis , endocrinology , biology , odds ratio , genetics , genotype , gene , breast cancer , cancer
Osteoporosis has a significant genetic component. The aromatase-dependent conversion of androgenic precursors is the main source of estrogens in postmenopausal women.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom