Prolonged Survival in Culture of Preantral Follicles from Polycystic Ovaries
Author(s) -
Lisa Webber,
S Stubbs,
Jaroslav Stark,
R. Margara,
Geoffrey Trew,
Stuart Lavery,
Kate Hardy,
Stephen Franks
Publication year - 2007
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2006-1422
Subject(s) - polycystic ovary , follicle , context (archaeology) , atresia , medicine , biology , endocrinology , ovary , folliculogenesis , ovarian follicle , andrology , pregnancy , obesity , lactation , genetics , insulin resistance , paleontology
In polycystic ovary syndrome (PCOS), an increased proportion of follicles leave the primordial (resting) pool and initiate growth. However, there is little evidence for a reduced reproductive life span (early menopause) in women with PCOS, suggesting that the dynamics of follicle growth, and of follicle loss by atresia, is altered in PCOS.
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