Corticotroph Tumor Progression after Adrenalectomy in Cushing’s Disease: A Reappraisal of Nelson’s Syndrome
Author(s) -
Guillaume Assié,
Hélène Bahurel,
Joël Coste,
S. Silvera,
M. Kujas,
Marie-Annick Dugué,
Foued Karray,
B. Dousset,
Jérôme Bertherat,
P. Legmann,
Xavier Bertagna
Publication year - 2006
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2006-1328
Subject(s) - corticotropic cell , medicine , context (archaeology) , cushing's disease , adrenalectomy , cushing disease , bilateral adrenalectomy , cushing syndrome , complication , endocrinology , pituitary tumors , disease , anterior pituitary , hormone , history , archaeology
Adrenalectomy is a radical treatment for hypercortisolism in Cushing's disease. However, it may lead to Nelson's syndrome, originally defined by the association of a pituitary macroadenoma and high plasma ACTH concentrations, a much feared complication.
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