Differential Effects of a Perioperative Hyperinsulinemic Normoglycemic Clamp on the Neurohumoral Stress Response during Coronary Artery Surgery | Zendy

Harry B. van Wezel | Zendy; Coert J. Zuurbier | Zendy; Evert de Jonge | Zendy; Eveline W. C. M. van Dam | Zendy; Johannes van Dijk | Zendy; Erik Endert | Zendy; Bas A.J.M. de Mol | Zendy; Eric Fliers | Zendy

Open Access

Differential Effects of a Perioperative Hyperinsulinemic Normoglycemic Clamp on the Neurohumoral Stress Response during Coronary Artery Surgery

Author(s) -

Harry B. van Wezel,

Coert J. Zuurbier,

Evert de Jonge,

Eveline W. C. M. van Dam,

Johannes van Dijk,

Erik Endert,

Bas A.J.M. de Mol,

Eric Fliers

Publication year - 2006

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2006-1199

Subject(s) - perioperative , medicine , clamp , cardiology , artery , fight or flight response , anesthesia , chemistry , computer science , clamping , biochemistry , computer vision , gene

Hyperglycemia in patients undergoing coronary artery bypass grafting (CABG) is associated with adverse outcome. Although insulin infusion strategies are increasingly used to improve outcome, a pathophysiological rationale is currently lacking. The present study was designed to quantify the effects of a perioperative hyperinsulinemic normoglycemic clamp on the neurohumoral stress response during CABG.

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