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Decreased Total and High Molecular Weight Adiponectin Are Independent Risk Factors for the Development of Type 2 Diabetes in Japanese-Americans
Author(s) -
Reiko Nakashima,
Nozomu Kamei,
Kiminori Yamane,
Shuhei Nakanishi,
Ayumu Nakashima,
Nobuoki Kohno
Publication year - 2006
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2006-1158
Subject(s) - adiponectin , adipokine , endocrinology , context (archaeology) , medicine , type 2 diabetes , diabetes mellitus , hormone , chemistry , biology , insulin resistance , paleontology
Adiponectin is a hormone secreted by adipocytes that acts as an antidiabetic adipokine. Adiponectin exists as multimers in plasma, and high molecular weight (HMW) adiponectin is particularly thought to be the active form of the protein.

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