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Thein VitroEffects of Resistin on the Innate Immune Signaling Pathway in Isolated Human Subcutaneous Adipocytes
Author(s) -
Christine M. Kusminski,
Nancy F. da Silva,
S. J. Creely,
Ffolliott M. Fisher,
Alison L. Harte,
Adam Baker,
Sudhesh Kumar,
Philip G. McTernan
Publication year - 2006
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2006-1151
Subject(s) - resistin , endocrinology , medicine , proinflammatory cytokine , innate immune system , adipokine , adipose tissue , insulin resistance , biology , inflammation , insulin , receptor
Obesity-associated inflammation is a contributory factor in the pathogenesis of type 2 diabetes mellitus (T2DM); the mechanisms underlying the progression to T2DM are unclear. The adipokine resistin has demonstrated proinflammatory properties in relation to obesity and T2DM.

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