Altered 24-Hour Blood Pressure Profiles in Children and Adolescents with Classical Congenital Adrenal Hyperplasia due to 21-Hydroxylase Deficiency
Author(s) -
Thomas M.K. Völkl,
Diemud Simm,
Jörg Dötsch,
Wolfgang Rascher,
Helmuth G. Dörr
Publication year - 2006
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2006-1069
Subject(s) - medicine , blood pressure , ambulatory blood pressure , congenital adrenal hyperplasia , body mass index , endocrinology , leptin , diastole , 21 hydroxylase , obesity , essential hypertension
Children and adolescents with classical congenital adrenal hyperplasia have been shown to be at risk for obesity associated with higher insulin and leptin levels. Because these factors are also known to cause hypertension, the aim of this study was to analyze 24-h blood pressure profiles and their relation to different clinical and laboratory parameters.
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