Associations of Body Size at Birth with Late-Life Cortisol Concentrations and Glucose Tolerance Are Modified by Haplotypes of the Glucocorticoid Receptor Gene | Zendy

Anna Rautanen | Zendy; Johan G. Eriksson | Zendy; Juha Kere | Zendy; Sture Andersson | Zendy; Clive Osmond | Zendy; Pentti Tienari | Zendy; Heikki Sairanen | Zendy; David J.P. Barker | Zendy; David I. W. Phillips | Zendy; Tom Forsén | Zendy; Eero Kajantie | Zendy

Open Access

Associations of Body Size at Birth with Late-Life Cortisol Concentrations and Glucose Tolerance Are Modified by Haplotypes of the Glucocorticoid Receptor Gene

Author(s) -

Anna Rautanen,

Johan G. Eriksson,

Juha Kere,

Sture Andersson,

Clive Osmond,

Pentti Tienari,

Heikki Sairanen,

David J.P. Barker,

David I. W. Phillips,

Tom Forsén,

Eero Kajantie

Publication year - 2006

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2006-1065

Subject(s) - endocrinology , medicine , haplotype , glucocorticoid , glucocorticoid receptor , odds ratio , diabetes mellitus , context (archaeology) , type 2 diabetes , birth weight , biology , pregnancy , genotype , genetics , gene , paleontology

Small body size at birth is associated with cardiovascular disease and type 2 diabetes in adult life. This link may be in part mediated by early-life programming of the hypothalamic-pituitary-adrenal axis (HPAA) function.

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