Testosterone Supplementation of Megestrol Therapy Does Not Enhance Lean Tissue Accrual in Men with Human Immunodeficiency Virus-Associated Weight Loss: A Randomized, Double-Blind, Placebo-Controlled, Multicenter Trial | Zendy

Kathleen Mulligan | Zendy; Robert Zackin | Zendy; Jamie H. Von Roenn | Zendy; Margaret A. Chesney | Zendy; Merrill J. Egorin | Zendy; Fred R. Sattler | Zendy; Constance A. Benson | Zendy; Tun Liu | Zendy; Triin Umbleja | Zendy; S. Shriver | Zendy; Richard J. Auchus | Zendy; Morris Schambelan | Zendy

Open Access

Testosterone Supplementation of Megestrol Therapy Does Not Enhance Lean Tissue Accrual in Men with Human Immunodeficiency Virus-Associated Weight Loss: A Randomized, Double-Blind, Placebo-Controlled, Multicenter Trial

Author(s) -

Kathleen Mulligan,

Robert Zackin,

Jamie H. Von Roenn,

Margaret A. Chesney,

Merrill J. Egorin,

Fred R. Sattler,

Constance A. Benson,

Tun Liu,

Triin Umbleja,

S. Shriver,

Richard J. Auchus,

Morris Schambelan

Publication year - 2006

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2006-0954

Subject(s) - megestrol , medicine , endocrinology , megestrol acetate , testosterone (patch) , lean body mass , placebo , weight loss , wasting , obesity , body weight , alternative medicine , pathology , cancer

Reduced energy intake is a primary factor in HIV-associated wasting. Megestrol acetate (MA) stimulates appetite and weight gain. However, much of the weight gained is fat, possibly as a result of MA-induced hypogonadism.

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