Fine Mapping of Genetic Susceptibility to Polycystic Ovary Syndrome on Chromosome 19p13.2 and Tests for Regulatory Activity | Zendy

Douglas R. Stewart | Zendy; Beth A. Dombroski | Zendy; Margrit Urbanek | Zendy; Wendy Ankener | Zendy; Kathryn G. Ewens | Zendy; Jennifer R. Wood | Zendy; Richard S. Legro | Zendy; Jerome F. Strauss | Zendy; Andrea Dunaif | Zendy; Richard S. Spielman | Zendy

Open Access

Fine Mapping of Genetic Susceptibility to Polycystic Ovary Syndrome on Chromosome 19p13.2 and Tests for Regulatory Activity

Author(s) -

Douglas R. Stewart,

Beth A. Dombroski,

Margrit Urbanek,

Wendy Ankener,

Kathryn G. Ewens,

Jennifer R. Wood,

Richard S. Legro,

Jerome F. Strauss,

Andrea Dunaif,

Richard S. Spielman

Publication year - 2006

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2006-0951

Subject(s) - polycystic ovary , biology , genetics , allele , transmission disequilibrium test , context (archaeology) , proband , linkage disequilibrium , genetic linkage , haplotype , gene , endocrinology , mutation , diabetes mellitus , insulin resistance , paleontology

Little is known about genes that contribute to polycystic ovary syndrome (PCOS). We previously found linkage and association of PCOS with the dinucleotide marker D19S884 in two independent sets of families; allele 8 of D19S884 confers increased risk.

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