Reduced Number of Circulating Endothelial Progenitor Cells in Hypogonadal Men | Zendy

Carlo Foresta | Zendy; Nicola Caretta | Zendy; Andrea Lana | Zendy; Luca De Toni | Zendy; Andrea Biagioli | Zendy; Alberto Ferlin | Zendy; Andrea Garolla | Zendy

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Reduced Number of Circulating Endothelial Progenitor Cells in Hypogonadal Men

Author(s) -

Carlo Foresta,

Nicola Caretta,

Andrea Lana,

Luca De Toni,

Andrea Biagioli,

Alberto Ferlin,

Andrea Garolla

Publication year - 2006

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2006-0763

Subject(s) - progenitor cell , immunocytochemistry , medicine , endocrinology , testosterone (patch) , androgen receptor , bone marrow , androgen , prospective cohort study , andrology , stem cell , biology , hormone , genetics , prostate cancer , cancer

Endothelial dysfunction seems to be the first step of the atherosclerotic process. In the past few years, it has been demonstrated that injured endothelial monolayer is restored by a premature pool of circulating progenitor cells (PCs) and a more mature one of circulating endothelial PCs (EPCs). Even though there is increasing evidence that estrogens play a beneficial role on EPCs and, even if debated, on the cardiovascular system, less is known about androgens.

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