A Common Mitochondrial DNA Variant and Increased Body Mass Index as Associated Factors for Development of Type 2 Diabetes: Additive Effects of Genetic and Environmental Factors
Author(s) -
ChiaWei Liou,
TsuKung Lin,
HsuHuei Weng,
Cheng-Feng Lee,
TzuLing Chen,
Yau–Huei Wei,
ShangDer Chen,
YaoChung Chuang,
ShaoWen Weng,
PeiWen Wang
Publication year - 2006
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2006-0653
Subject(s) - mitochondrial dna , body mass index , type 2 diabetes , genetics , biology , index (typography) , evolutionary biology , diabetes mellitus , gene , endocrinology , computer science , world wide web
The suggested correlation between a T-to-C transition at the nucleotide 16189 in mitochondrial DNA (mtDNA) with increasing insulin resistance and adult-onset diabetes mellitus (DM) is debatable.
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