Potent Inhibitory Effects of Type I Interferons on Human Adrenocortical Carcinoma Cell Growth | Zendy

Peter M. van Koetsveld | Zendy; Giovanni Vitale | Zendy; Wouter W. de Herder | Zendy; Richard A. Feelders | Zendy; Katy van der Wansem | Zendy; Marlijn Waaijers | Zendy; Casper H.J. van Eijck | Zendy; ErnstJan M. Speel | Zendy; Ed Croze | Zendy; AartJan van der Lely | Zendy; Steven W. J. Lamberts | Zendy; Leo J. Hofland | Zendy

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Potent Inhibitory Effects of Type I Interferons on Human Adrenocortical Carcinoma Cell Growth

Author(s) -

Peter M. van Koetsveld,

Giovanni Vitale,

Wouter W. de Herder,

Richard A. Feelders,

Katy van der Wansem,

Marlijn Waaijers,

Casper H.J. van Eijck,

ErnstJan M. Speel,

Ed Croze,

AartJan van der Lely,

Steven W. J. Lamberts,

Leo J. Hofland

Publication year - 2006

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2006-0620

Subject(s) - adrenocortical carcinoma , apoptosis , cell growth , endocrinology , medicine , cell culture , growth inhibition , cell cycle , cell , ic50 , biology , cancer research , cancer , biochemistry , genetics

Adrenocortical carcinoma (ACC) is a rare tumor with a poor prognosis. Despite efforts to develop new therapeutic regimens for metastatic ACC, surgery remains the mainstay of treatment. Interferons are known to exert tumor-suppressive effects in several types of human cancer.

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