In Men, Peripheral Estradiol Levels Directly Reflect the Action of Estrogens at the Hypothalamo-Pituitary Level to Inhibit Gonadotropin Secretion
Author(s) -
Garrett Raven,
Frank H. de Jong,
JeanMarc Kaufman,
Willem de Ronde
Publication year - 2006
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2006-0462
Subject(s) - medicine , endocrinology , testosterone (patch) , aromatase , gonadotropin , estrogen , hypothalamic–pituitary–gonadal axis , hypothalamus , luteinizing hormone , letrozole , aromatase inhibitor , chemistry , biology , hormone , cancer , breast cancer
Estradiol inhibits gonadotropin release in men by an action at the hypothalamus and pituitary. Because of the tissue-specific regulation of aromatase, peripheral estradiol levels may not reflect brain estradiol concentrations.
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