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Effect on Adult Height of Pubertal Growth Hormone Retesting and Withdrawal of Therapy in Patients with Previously Diagnosed Growth Hormone Deficiency
Author(s) -
Stefano Zucchini,
Piero Pirazzoli,
Federico Baronio,
Monia Gennari,
Milva Orquidea Bal,
Antonio Balsamo,
Stefano Gualandi,
Alessandro Cicognani
Publication year - 2006
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2006-0383
Subject(s) - growth hormone , growth hormone deficiency , normalization (sociology) , endocrinology , context (archaeology) , medicine , secretion , hormone , biology , paleontology , sociology , anthropology
GH replacement therapy in GH-deficient (GHD) patients is usually continued until adult height despite the fact that most of these subjects display a normal secretion when retested at the end of growth. Puberty is the most likely time for normalization of GH secretion.

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