Effect on Adult Height of Pubertal Growth Hormone Retesting and Withdrawal of Therapy in Patients with Previously Diagnosed Growth Hormone Deficiency
Author(s) -
Stefano Zucchini,
Piero Pirazzoli,
Federico Baronio,
Monia Gennari,
Milva Orquidea Bal,
Antonio Balsamo,
Stefano Gualandi,
Alessandro Cicognani
Publication year - 2006
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2006-0383
Subject(s) - growth hormone , growth hormone deficiency , normalization (sociology) , endocrinology , context (archaeology) , medicine , secretion , hormone , biology , paleontology , sociology , anthropology
GH replacement therapy in GH-deficient (GHD) patients is usually continued until adult height despite the fact that most of these subjects display a normal secretion when retested at the end of growth. Puberty is the most likely time for normalization of GH secretion.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom