Ribonucleic Acid Interference Targeting S100A4 (Mts1) Suppresses Tumor Growth and Metastasis of Anaplastic Thyroid Carcinoma in a Mouse Model
Author(s) -
Yufei Shi,
Minjing Zou,
Katharine Collison,
Essa Y. Baitei,
Zaha Al-Makhalafi,
Nadir R. Farid,
Futwan AlMohanna
Publication year - 2006
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2006-0155
Subject(s) - small hairpin rna , gene knockdown , cancer research , anaplastic thyroid cancer , metastasis , rna interference , cell growth , thyroid carcinoma , transfection , paclitaxel , thyroid cancer , apoptosis , biology , medicine , cancer , cell culture , thyroid , rna , biochemistry , genetics , gene
The characteristic feature of malignant neoplasm is invasion and metastasis. Despite advances in the management of thyroid carcinoma and other solid tumors, metastasis continues to be the most significant cause in cancer mortality.
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