Weight-Adjusted Genome Scan Analysis for Mapping Quantitative Trait Loci for Menarchal Age
Author(s) -
Anya Rothenbühler,
Delphine Fradin,
Simon Heath,
Hervé Lefèvre,
Claire Bouvattier,
M Lathrop,
Pierre Bougnères
Publication year - 2006
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2006-0150
Subject(s) - quantitative trait locus , trait , genome scan , genetics , biology , microsatellite , genome , context (archaeology) , menarche , genetic linkage , linkage (software) , gene , allele , endocrinology , paleontology , computer science , programming language
Twin and family studies indicate that genetic factors contribute to the variability of age at menarche (AAM), a multifactorial trait of major importance to human reproductive success. Individual variability of premenarcheal fatness is known to be an important determinant of AAM.
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