Comparison of Confirmatory Tests for the Diagnosis of Primary Aldosteronism
Author(s) -
Paolo Mulatero,
Alberto Milan,
Francesco Fallo,
Giuseppe Regolisti,
Francesca Pizzolo,
Carlos Fardella,
Lorena Mosso,
Lisa Marafetti,
Franco Veglio,
Mauro Maccario
Publication year - 2006
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2006-0078
Subject(s) - primary aldosteronism , medicine , fludrocortisone , aldosterone , context (archaeology) , secondary hypertension , adenoma , hyperaldosteronism , endocrinology , receiver operating characteristic , gastroenterology , urology , hydrocortisone , blood pressure , biology , paleontology
Primary aldosteronism (PA) is the most frequent form of secondary hypertension, accounting for up to 5-10% of all hypertensive patients, and the diagnosis of PA can present an important challenge for the clinician. After a positive screening test, the diagnosis is confirmed by a suppression test, often an iv saline load test (SLT) or a fludrocortisone suppression test (FST). The FST is considered by many to be the most reliable but is more complex and expensive.
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