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Changes in Insulin Sensitivity and Glucose and Bone Metabolism over Time in Patients with Asymptomatic Primary Hyperparathyroidism
Author(s) -
Semra Aytürk,
Alptekin Gürsoy,
Neslihan Başçıl Tütüncü,
Derun Taner Ertuğrul,
Nilgün Güvener Demirağ
Publication year - 2006
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2005-2825
Subject(s) - asymptomatic , medicine , endocrinology , primary hyperparathyroidism , diabetes mellitus , insulin resistance , glucose homeostasis , hyperparathyroidism , calcium metabolism , gastroenterology , calcium
The clinical profile of asymptomatic primary hyperparathyroidism (PHPT) has shifted from a symptomatic disorder toward a more subtle, asymptomatic state. The lack of knowledge about the natural course of asymptomatic PHPT contributes to the controversy regarding the optimal management of these patients. The aim of this study is to evaluate the natural course of calcium and glucose metabolism abnormalities, insulin sensitivity, and bone mineral density (BMD) in subjects with asymptomatic PHPT over 18 months.

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