Ghrelin Potentiates Growth Hormone Secretion Driven by Putative Somatostatin Withdrawal and Resists Inhibition by Human Corticotropin-Releasing Hormone | Zendy

Johannes D. Veldhuis | Zendy; Ali Iranmanesh | Zendy; Kristi L. Mielke | Zendy; John J. Miles | Zendy; Paul C. Carpenter | Zendy; Cyril Y. Bowers | Zendy

Open Access

Ghrelin Potentiates Growth Hormone Secretion Driven by Putative Somatostatin Withdrawal and Resists Inhibition by Human Corticotropin-Releasing Hormone

Author(s) -

Johannes D. Veldhuis,

Ali Iranmanesh,

Kristi L. Mielke,

John J. Miles,

Paul C. Carpenter,

Cyril Y. Bowers

Publication year - 2006

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2005-2718

Subject(s) - ghrelin , endocrinology , medicine , somatostatin , saline , arginine , peptide hormone , secretagogue , liter , hormone , bolus (digestion) , chemistry , secretion , amino acid , biochemistry

Ghrelin is a 28-amino acid, Ser(3)-octanoylated peptide that stimulates GH secretion in vivo and in vitro. Beyond the capability of ghrelin to synergize with GHRH, little is known about multipeptide modulation of ghrelin's actions in humans.

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