Elevated Serum Levels of Pigment Epithelium-Derived Factor in the Metabolic Syndrome | Zendy

Shoichi Yamagishi | Zendy; Hisashi Adachi | Zendy; Akio Abe | Zendy; Takako Yashiro | Zendy; Mika Enomoto | Zendy; Kumiko Furuki | Zendy; Asuka Hino | Zendy; Yuko Jinnouchi | Zendy; Katsuhiko Takenaka | Zendy; Takanori Matsui | Zendy; Kazuo Nakamura | Zendy; Tsutomu Imaizumi | Zendy

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Elevated Serum Levels of Pigment Epithelium-Derived Factor in the Metabolic Syndrome

Author(s) -

Shoichi Yamagishi,

Hisashi Adachi,

Akio Abe,

Takako Yashiro,

Mika Enomoto,

Kumiko Furuki,

Asuka Hino,

Yuko Jinnouchi,

Katsuhiko Takenaka,

Takanori Matsui,

Kazuo Nakamura,

Tsutomu Imaizumi

Publication year - 2006

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2005-2654

Subject(s) - pedf , metabolic syndrome , medicine , uric acid , endocrinology , waist , risk factor , diabetes mellitus , angiogenesis , physiology , obesity

Pigment epithelium-derived factor (PEDF), a potent inhibitor of angiogenesis with neuronal differentiating activity, inhibits endothelial cell injury in vitro, thus suggesting the involvement of PEDF in atherosclerosis. Therefore, elucidating the relationship between serum levels of PEDF and coronary risk factors could provide a clue to understanding the pathophysiological role of PEDF in vivo.

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