Decreased Androgen Receptor Gene Methylation in Premature Pubarche: A Novel Pathogenetic Mechanism? | Zendy

Alessandra Vottero | Zendy; Marzia Capelletti | Zendy; Silvia Giuliodori | Zendy; Isabella Viani | Zendy; M. Ziveri | Zendy; Tauro Maria Neri | Zendy; Sergio Bernasconi | Zendy; Lucia Ghizzoni | Zendy

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Decreased Androgen Receptor Gene Methylation in Premature Pubarche: A Novel Pathogenetic Mechanism?

Author(s) -

Alessandra Vottero,

Marzia Capelletti,

Silvia Giuliodori,

Isabella Viani,

M. Ziveri,

Tauro Maria Neri,

Sergio Bernasconi,

Lucia Ghizzoni

Publication year - 2006

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - Uncategorized

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2005-2354

Subject(s) - androgen receptor , medicine , endocrinology , methylation , context (archaeology) , dna methylation , androgen , population , pubic hair , testosterone (patch) , biology , gene expression , gene , genetics , cancer , hormone , prostate cancer , paleontology , environmental health

Several studies found links between DNA methylation and gene expression. In patients with idiopathic hirsutism, a preferential methylation of the of shorter androgen receptor (AR) alleles was hypothesized to be responsible for the abnormal hair growth.

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