An Increased Coronary Risk Is Paradoxically Associated with Common Cholesteryl Ester Transfer Protein Gene Variations That Relate to Higher High-Density Lipoprotein Cholesterol: A Population-Based Study
Author(s) -
S. E. Borggreve,
Hans L. Hillege,
Bruce H. R. Wolffenbuttel,
Paul E. de Jong,
Mike W. Zuurman,
Gerrit van der Steege,
Arie van Tol,
Robin P.F. Dullaart
Publication year - 2006
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2005-2322
Subject(s) - cholesterylester transfer protein , cholesterol , high density lipoprotein , medicine , reverse cholesterol transport , lipoprotein , population , cholesteryl ester , gene transfer , endocrinology , gene , chemistry , biochemistry , environmental health
Several cholesteryl ester transfer protein (CETP) polymorphisms affect high-density lipoprotein (HDL) cholesterol, but the impact of CETP gene variants on incident coronary disease in the general population is uncertain after correction for their effect on HDL cholesterol.
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