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Hyponatremia [serum sodium concentration ([Na(+)]), &lt;135 mEq/liter] is the most common fluid and electrolyte abnormality among hospitalized patients. It is frequently caused by the inappropriate release of arginine vasopressin.

the journal of clinical endocrinology and metabolism/journal of clinical endocrinology and metabolism

Efficacy and Safety of Oral Conivaptan: A V<sub>1A</sub>/V<sub>2</sub>Vasopressin Receptor Antagonist, Assessed in a Randomized, Placebo-Controlled Trial in Patients with Euvolemic or Hypervolemic Hyponatremia

Efficacy and Safety of Oral Conivaptan: A V1A/V2Vasopressin Receptor Antagonist, Assessed in a Randomized, Placebo-Controlled Trial in Patients with Euvolemic or Hypervolemic Hyponatremia

Efficacy and Safety of Oral Conivaptan: A V_1A/V₂Vasopressin Receptor Antagonist, Assessed in a Randomized, Placebo-Controlled Trial in Patients with Euvolemic or Hypervolemic Hyponatremia