Ghrelin Secretion in Preterm Neonates Progressively Increases and Is Refractory to the Inhibitory Effect of Food Intake
Author(s) -
Simonetta Bellone,
Roberto Baldelli,
Giorgio Radetti,
Anna Rapa,
Daniela Vivenza,
Antonella Petri,
Silvia Savastio,
Mauro Zaffaroni,
Fabio Broglio,
Ezio Ghigo,
Gianni Bona
Publication year - 2006
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2005-2185
Subject(s) - ghrelin , orexigenic , medicine , endocrinology , cord blood , gestational age , leptin , hormone , obesity , pregnancy , biology , neuropeptide y receptor , neuropeptide , receptor , genetics
Ghrelin, a natural GH secretagogue, is mainly characterized by nonendocrine activities such as orexigenic effect and modulation of the endocrine and metabolic response to variations in energy balance. Ghrelin levels have been reported to be negatively associated with insulin secretion, enhanced in anorexia, and reduced in obesity. Ghrelin levels in newborns were shown to be similar to those found in children and adults without any gender-related difference.
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