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Follicle Luteinization in Hyperandrogenic Follicles of Polycystic Ovary Syndrome Patients Undergoing Gonadotropin Therapy forin VitroFertilization
Author(s) -
Shu C. Foong,
David H. Abbott,
Michael A. Zschunke,
Timothy G. Lesnick,
J.L. Phy,
Daniel A. Dumesic
Publication year - 2006
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2005-2142
Subject(s) - polycystic ovary , endocrinology , medicine , hyperandrogenism , gonadotropin , follicle , ovarian follicle , biology , ovary , anovulation , in vitro fertilisation , follicle stimulating hormone , oocyte , basal (medicine) , insulin , hormone , insulin resistance , luteinizing hormone , pregnancy , embryo , genetics , microbiology and biotechnology
Polycystic ovary syndrome (PCOS) is a reproductive disorder of ovarian hyperandrogenism and insulin resistance characterized by abnormal luteinization of small follicles. After exposure to GnRH analog/FSH stimulation for in vitro fertilization (IVF), however, it is unclear whether such PCOS follicles remain abnormally luteinized during the resumption of oocyte maturation in vivo.

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